| 1 |  Joseph Edelman Perceptive Advisors LLC | | 108,000 | $19.16M | HOLD |
| 2 |  Israel Englander Millennium Management LLC | | 826,376 | $146.63M | HOLD |
| 3 |  Steve Cohen Point72 Asset Management LP | | 219,468 | $38.94M | HOLD |
| 4 |  Dmitry Balyasny Balyasny Asset Management LP | | 167,274 | $29.68M | HOLD |
| 5 |  David E. Shaw D.E. Shaw & Co LP | | 360,669 | $64.00M | HOLD |
| 6 |  Jim Simons (Estate) Renaissance Technologies LLC | | 103,900 | $18.44M | HOLD |
| 7 |  T. Rowe Price T. Rowe Price Associates Inc | | 502,120 | $89.10M | HOLD |
| 8 |  Vanguard Vanguard Group Inc | | 3,310,519 | $587.42M | HOLD |
| 9 |  JPMorgan Chase JPMorgan Chase & Co | | 758,587 | $134.60M | HOLD |
| 10 |  | | 2,813,989 | $499.31M | HOLD |
| 11 |  Ray Dalio Bridgewater Associates LP | | 11,348 | $2.01M | HOLD |
| 12 |  Goldman Sachs Goldman Sachs Asset Management LP | | 329,135 | $58.40M | HOLD |
| 13 |  | | 628,766 | $111.57M | HOLD |
| 14 |  State Street State Street Global Advisors | | 764,839 | $135.71M | HOLD |
| 15 |  Cliff Asness AQR Capital Management LLC | | 40,165 | $7.13M | HOLD |
| 16 |  Ken Griffin Citadel Advisors LLC | | 82,100 | $14.57M | HOLD |
| 17 |  Joel Greenblatt Gotham Asset Management LLC | | 2,017 | $357,896 | HOLD |
| 18 |  Norges Bank Norges Bank Investment Management | | 56,237 | $9.98M | HOLD |
IRTC