| 1 |  Lee Ainslie Maverick Capital Ltd | | 4,195,089 | $263.24M | HOLD |
| 2 |  David E. Shaw D.E. Shaw & Co LP | | 24,312,352 | $1.53B | HOLD |
| 3 |  Two Sigma Two Sigma Investments LP | | 9,411,231 | $590.55M | HOLD |
| 4 |  Jim Simons (Estate) Renaissance Technologies LLC | | 3,152,005 | $197.79M | HOLD |
| 5 |  Steve Cohen Point72 Asset Management LP | | 3,687,315 | $231.38M | HOLD |
| 6 |  Fidelity (FMR) Fidelity Management & Research | | 74,226,395 | $4.66B | HOLD |
| 7 |  National Pension Service National Pension Service | | 3,698,745 | $232.10M | HOLD |
| 8 |  Cliff Asness AQR Capital Management LLC | | 5,239,836 | $327.28M | HOLD |
| 9 |  State Street State Street Global Advisors | | 67,986,847 | $4.27B | HOLD |
| 10 |  | | 131,822,037 | $8.27B | HOLD |
| 11 |  Goldman Sachs Goldman Sachs Asset Management | | 18,891,624 | $1.19B | HOLD |
| 12 |  JPMorgan Chase JPMorgan Asset Management | | 33,350,157 | $2.10B | HOLD |
| 13 |  Dmitry Balyasny Balyasny Asset Management LP | | 1,356,133 | $85.10M | HOLD |
| 14 |  Israel Englander Millennium Management LLC | | 4,337,804 | $240.82M | HOLD |
| 15 |  Mario Gabelli GAMCO Investors Inc | | 155,146 | $9.74M | HOLD |
| 16 |  Joel Greenblatt Gotham Asset Management LLC | | 482,978 | $30.31M | HOLD |
| 17 |  Paul Tudor Jones Tudor Investment Corp | | 632,552 | $39.69M | HOLD |
| 18 |  T. Rowe Price T. Rowe Price Associates | | 7,873,368 | $494.05M | HOLD |
| 19 |  Stephen Mandel Lone Pine Capital LLC | | 104,655 | $6.57M | HOLD |
| 20 |  Ken Griffin Citadel Advisors LLC | | 4,217,314 | $264.64M | HOLD |
| 21 |  Ray Dalio Bridgewater Associates LP | | 76,992 | $4.83M | HOLD |
| 22 |  Ken Fisher Fisher Asset Management LLC | | 450,603 | $28.28M | HOLD |
| 23 |  | | 15,000 | $941,250 | HOLD |
BSX