| 1 |  Two Sigma Two Sigma Investments LP | | 7,342,096 | $216.52M | HOLD |
| 2 |  David E. Shaw D.E. Shaw & Co LP | | 5,182,759 | $152.84M | HOLD |
| 3 |  | | 28,045,311 | $827.06M | HOLD |
| 4 |  Ken Griffin Citadel Advisors LLC | | 6,896,500 | $203.38M | HOLD |
| 5 |  Paul Tudor Jones Tudor Investment Corp | | 485,000 | $14.30M | HOLD |
| 6 |  Jim Simons (Estate) Renaissance Technologies LLC | | 568,400 | $16.76M | HOLD |
| 7 |  Vanguard Vanguard Group Inc | | 41,584,782 | $1.23B | HOLD |
| 8 |  | | 32,505,733 | $958.59M | HOLD |
| 9 |  State Street State Street Global Advisors | | 16,365,478 | $482.62M | HOLD |
| 10 |  Philippe Laffont Coatue Management LLC | | 200,000 | $5.90M | HOLD |
| 11 |  Goldman Sachs Goldman Sachs Asset Management LP | | 3,950,619 | $116.50M | HOLD |
| 12 |  Norges Bank Norges Bank Investment Management | | 2,702,832 | $79.71M | HOLD |
| 13 |  Steve Cohen Point72 Asset Management LP | | 178,000 | $5.25M | HOLD |
| 14 |  Israel Englander Millennium Management LLC | | 403,635 | $11.90M | HOLD |
| 15 |  Dmitry Balyasny Balyasny Asset Management LP | | 76,400 | $2.25M | HOLD |
| 16 |  JPMorgan Chase JPMorgan Chase & Co | | 1,013,884 | $29.90M | HOLD |
| 17 |  Ray Dalio Bridgewater Associates LP | | 15,181 | $447,688 | HOLD |
| 18 |  T. Rowe Price T. Rowe Price Associates Inc | | 494,013 | $14.57M | HOLD |
| 19 |  Cliff Asness AQR Capital Management LLC | | 12,010 | $354,187 | HOLD |
MRNA