| 1 |  George Soros Soros Fund Management LLC | | 1,569,507 | $24.14M | HOLD |
| 2 |  Jim Simons (Estate) Renaissance Technologies LLC | | 3,337,533 | $51.33M | HOLD |
| 3 |  Two Sigma Two Sigma Investments LP | | 1,632,610 | $25.11M | HOLD |
| 4 |  Dmitry Balyasny Balyasny Asset Management LP | | 567,389 | $8.73M | HOLD |
| 5 |  Israel Englander Millennium Management LLC | | 972,481 | $14.96M | HOLD |
| 6 |  Mario Gabelli GAMCO Investors Inc | | 40,000 | $615,200 | HOLD |
| 7 |  Joel Greenblatt Gotham Asset Management LLC | | 99,256 | $1.53M | HOLD |
| 8 |  David E. Shaw D.E. Shaw & Co LP | | 632,594 | $9.73M | HOLD |
| 9 |  Paul Tudor Jones Tudor Investment Corp | | 187,161 | $2.88M | HOLD |
| 10 |  | | 16,307,312 | $250.81M | HOLD |
| 11 |  Goldman Sachs Goldman Sachs Asset Management LP | | 2,153,979 | $33.13M | HOLD |
| 12 |  State Street State Street Global Advisors | | 7,164,163 | $110.18M | HOLD |
| 13 |  Ken Fisher Fisher Asset Management LLC | | 569,018 | $8.75M | HOLD |
| 14 |  Vanguard Vanguard Group Inc | | 8,027,448 | $123.46M | HOLD |
| 15 |  Steve Cohen Point72 Asset Management LP | | 92,241 | $1.42M | HOLD |
| 16 |  Cliff Asness AQR Capital Management LLC | | 156,317 | $2.40M | HOLD |
| 17 |  JPMorgan Chase JPMorgan Asset Management | | 674,643 | $10.38M | HOLD |
| 18 |  Ken Griffin Citadel Advisors LLC | | 116,684 | $1.79M | HOLD |
| 19 |  T. Rowe Price T. Rowe Price Associates Inc | | 102,996 | $1.58M | HOLD |
| 20 |  | | 105,128 | $1.62M | HOLD |
DVAX